"Instant Notes in Bioinformatics, Second Edition" illustrates how bioinformatics can be applied by all informatics students to most aspects of the life sciences. The book is divided into three parts: Part One - an introduction to bioinformatics and its application to biology; Part Two - the Building Blocks of Informatics - the physical, mathematical, statistical and computational bases of bioinformatics, with the use of biological examples; and, Part Three - the Biological Application Domains - divided into three subgroups, molecular biology, metabolism/anatomy/physiology, and complex information sources. The interconnections between the Building Blocks and Application areas throughout the text are highlighted, illustrating the foundational importance of, and reliance on, the Building Blocks from all of the Application areas.