Thanks to Einstein's relativity theories, our notions of space and time underwent profound revisions about a 100 years ago. The resulting interplay between geometry and physics has dominated all of fundamental physics since then. This volume contains contributions from leading researchers, worldwide, who have thought deeply about the nature and consequences of this interplay. The articles take a long-range view of the subject and distill the most important advances in broad terms, making them easily accessible to non-specialists. The first part is devoted to a summary of how relativity theories were born (J Stachel). The second part discusses the most dramatic ramifications of general relativity, such as black holes (P Chrusciel and R Price), space-time singularities (H Nicolai and A Rendall), gravitational waves (P Laguna and P Saulson), the large scale structure of the cosmos (T Padmanabhan); experimental status of this theory (C Will) as well as its practical application to the GPS