The third volume of the "Practice of Intramedullary Locked Nails" places a special focus on recent advancements in understanding the biology of fracture healing of long bones, the emerging technologies that further enhance the minimally invasive nature of closed treatment of fractures, and the availability of various surgical techniques in intramedullary fixation. The application of new technology in prevention of infection and application of the intramedullary fixation of fractures in pediatric and adolescent patients are also described. The contributors to this volume are from different well-known trauma centers and are pioneer surgeons in the development and practice of intramedullary locked nails.