When Isabel's mother turned forty-one, she locked herself in the garage and sat in a Dodge Dart with the engine running. Now, Isabel is turning forty-one, and her father, sister, and seven-year-old niece are flying in to Colorado to help her get through the day-even though she never asked for help. In fact, her family may be the ones who need help. And as Izzy is flooded with memories of her past, and wonders about her future, her unsteady marriage, and her dwindling chances of having a baby, the here and now demands her attention, as she is forced to confront a choice that breaks her heart, and may tear her family apart.